Ipertermia efficace nel carcinoma renale

L'articolo in questione presenta una esperienza eseguita in Russia di combinazione di un trattamento chemioterapico antiblastico ed ipertermia total body in 12 giovani pazienti affetti da neoplasia renale localmente avanzata sottoposta a resezione chirurgica. La sopravvivenza a 10 anni si attesta al 91%.

Dr. Carlo Pastore

Vopr Onkol. 2011;57(2):241-4.

[Renal carcinoma in childhood].
[Article in Russian]

Ismail-zade RS.

Abstract

Our data on treatment of renal carcinoma in 12 children (1996-2006) are presented. Nephrectomy and lymph node dissection was carried out in all patients; adjuvant chemotherapy (doxorubicin, interferon alpha2b (IBF alpha2b/Intron A) with concomitant whole body hyperthermia (systemic thermobiochemotherapy--7. Overall 10-year survival in all patients was 91% (median 42.3 months). Survival rate in cases of advanced renal carcinoma who received postoperative thermobiochemotherapy was 86% (median 54.8 months). Our results suggest that thermobiochemotherapy be indicated in children with advanced renal carcinoma.